The CZ Biohub Orgnalle Box

Goals:

Provide a shared resource of organelle-tagged cell lines for the community to aggregate, share, and access data and observations, fostering open collaboration and accelerating discovery.

Pilot release (Q1 2025)

We will release two tagged cell lines (A549: 16 organelles/22 markers and HEK293: 36 cell lines/19 organelles). The box will include cells, QC results, and SOPs (Maintenance, Organelle-IP, Labeling, Imaging). Groups can use and modify cells at will. In return, we request that the observations/results be shared with CZ Biohub SF. We are open to collaboration with the community on data analysis.

Please reach out to Arias group to request cell lines.